If you are using our Mac client app to control a computer remotely which is running either the Mac Streamer or the Windows Streamer, and you want to use a combination of keys for "shortcut" purposes, you will need to use the Fn key together with those combination keys when they include the Shift key or the Alt (Option) key.
For example, during a Splashtop connection session:
1. If you want to use the Shift+F4 key combination to put Windows in Sleep mode (for a Lenovo Windows NB), you would need to press Fn+Shift+F4 on the Mac keyboard.
2. If you want to use the Alt+F4 key combination to close a window on a remote computer running the Windows Streamer, you would need to press Fn+Option+F4 on the Mac keyboard.
Other keys, like Ctrl, Command (='Win key' for Windows), are the same between Mac and Windows.
In addition, if you are controlling another Mac, the Global hotkey on the Mac keyboard like 'Command'+Tab (change app), the "Enable access for assistive devices" option must first be enabled; then your Splashtop app can successfully send it to the remote computer running the Mac Streamer
Here is how to find the option "Enable access for assistive devices" —
For OS X 10.6 (Snow Leopard) and 10.7 (Lion):
System Preferences --> Universal Access --> Enable access for assistive devices
For OS X 10.8 (Mountain Lion):
System Preferences --> Accessibility --> Enable access for assistive devices